| Drug/ Poisons & Antidotes | |
|---|---|
| Drugs/isons | Antidotes |
| Acetaminophen | NAC (N-acetyl-L-cysteine) |
| Methanol/Ethylene glycol | Ethanol, Fomepizol (potent inhibitor of ADH) 4-methylpyrazole |
| Heparine | Protamine sulphate |
| Warfarin | Vitamin k, Fresh frozen Plasma |
| TCA's | Physiostigmine, Benzodiazepines |
| Beta antagonists (Proprenolol) | Glucagon, Epinephrine |
| Calcium antagonistis (CCBs) | calcium gluconate |
| Cocaine | BZD's for seizuries; labetalol for hypertension;Neuroleptic for psychosis |
| Digoxin | Digibind |
| iron | Desferrioxamine, Deferiprone |
| Lead | DMSA(2,3-di mercaptosuccinic acid), EDTA (disodium Ca-edetate) BAL |
| Mercury&Arsenic | DMPS(2,3-dimercapto-1-propane sulphonate), penicillamine |
| Copper | Penicillamine, trientine |
| Manganese | Calcium disodium edentate |
| Isoniazid | Pyridoxine (reverses INH induced seizures) |
| Opiates | Naloxone, Nalefene |
| Organophosphates | Atropine, Pralidoxamine (ChE reactivator) |
| Salicylates | Activated Charcoal |
| Theophylline | Charcoal, Beta Antagonists |
| Glucose&Insulin | sodium polystyrene sulfonate(Cationic exchange resin) |
| Snake bite | Specific venom antisera, Atropine +neostigmone |
| Paracetamol | N-acetylcysteine, Methionine |
| Belladonna Poisoning/overdose of phenothiazenes drugs |
Physostimine |
| Mushroom Poisoning | Atropine(rad onset), Thiotic acid (delayed onset) |
| Carbon monoxide | 100% oxygen |
| Methotrexate overdose | Leucovorin (folinic acid |
| Competitive neuromuscular blockers(D-tubocurarine) |
Neostigmine |
| Cisplatin induced nephrotoxicity | Amifostine |
| Cyclophosphamde induced cystitis (bladder damage) |
Anemia, Weight gainMesna (Mercapto ethane sulphonate) |
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Friday, 24 February 2023
Drug/ Poisons & Antidotes
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