CEFIXIME Antibiotic - Drug Informics

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Monday, 3 October 2022

CEFIXIME Antibiotic

About CEFIXIME

CEFIXIME belongs to a group of cephalosporin antibiotics. It is used to treat susceptible organisms (bacteria)-caused infections of the ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia) and urinary system (cystitis and kidney infections). Additionally, it is also prescribed to treat uncomplicated gonorrhoea (cervical/urethral). 

CEFIXIME contains Cefixime that works by inhibiting of cell wall synthesis. In turn, CEFIXIME weakens and destroys the bacterial cell wall, leading to death. As a result, CEFIXIME helps to treat bacterial infections.

Take CEFIXIME as directed by the physician. Sometimes, you may experience common side effects such as diarrhoea, nausea, loose stools, abdominal pain, dyspepsia, indigestion, and vomiting. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take CEFIXIME if you are allergic to cefixime, other cephalosporin antibiotics, or any other ingredients of this medicine. Before starting the CEFIXIME, please inform your doctor if you have colitis (inflammation of the colon's inner lining), renal dysfunction, liver disease, and seizure disorders. Do not take this medicine on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking the CEFIXIME. Drive only if you are alert as CEFIXIME may cause dizziness.

Uses of CEFIXIME

Bacterial Infections

Medicinal Benefits

CEFIXIME is a short-term medication for a wide range of bacterial infections. It prevents the growth of bacteria by stopping the formation of a protective covering which is vital for its growth. It prevents and treats bacterial infections like ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia) and urinary system (cystitis and kidney infections). Additionally, it is also prescribed to treat uncomplicated gonorrhoea (cervical/urethral).

 

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole. Liquid/Suspension: Shake the bottle well before use. Check the label for directions and take CEFIXIME in doses as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack. Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CEFIXIME

  • Diarrhoea
  • Nausea
  • Loose stools
  • Abdominal pain
  • Dyspepsia or indigestion
  • Vomiting

 

In-Depth Precautions and Warning

Drug Warnings

CEFIXIME has occasionally been associated with hypersensitive reactions that result in shock and mortality. If a reaction happens, stop using it. Do not take CEFIXIME if you are allergic to Cefixime or other cephalosporin antibiotics, or any of the other ingredients of this medicine. Talk to the doctor before taking CEFIXIME if you have seizures, liver or renal dysfunction, heart disorder, and inflammation of the colon's inner lining (colitis). Do not take CEFIXIME without first consulting the doctor if you are pregnant, planning for pregnancy or breastfeeding. Drive only if you are alert as CEFIXIME may cause dizziness. CEFIXIME may interact with certain tests such as glucose (sugar) in urine and give unusual results. Therefore, inform the doctor that you are using CEFIXIME before undergoing any tests.

Drug Interactions

Drug-Drug Interactions: CEFIXIME may interact with certain vaccines (BCG, cholera vaccine, typhoid vaccine), anticoagulant medications (warfarin), and anticonvulsant medications (carbamazepine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: CEFIXIME may interact with disease conditions, including colitis (inflammation of the colon's inner lining), renal dysfunction, liver disease, and seizure disorders.

 

Safety Advice

  • Safety Warning

    Alcohol

    It is unknown whether CEFIXIME interacts with alcohol. However, as a precautionary measure, it is advisable not to take or limit alcohol.

  • Safety Warning

    Pregnancy

    CEFIXIME should not be used during pregnancy unless clearly necessary. Your doctor will weigh the benefits and potential risks before prescribing it. Please consult your doctor.

  • Safety Warning

    Breast Feeding

    CONSULT YOUR DOCTOR

    CEFIXIME should be administered to nursing mothers only if the benefits of therapy are judged to outweigh the potential risks to the infant. Hence it is best to consult a doctor before taking the CEFIXIME.

  • Safety Warning

    Driving

    Caution should be exercised; CEFIXIME usually causes drowsiness and confusion, affecting driving ability.

  • Safety Warning

    Liver

    CEFIXIME to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

  • Safety Warning

    Kidney

    CEFIXIME to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

 

Habit Forming

No

Diet & Lifestyle Advise

  • After taking the full course of CEFIXIME, probiotics should be taken to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of CEFIXIME.
  • Avoid alcoholic beverages with CEFIXIME as it can dehydrate and affect your sleep. this can make it harder for your body to aid the CEFIXIME in fighting off infections.

 

 Patients Concern

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E.coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

 

 Trade/Band name:

  1. Rx                                                                            Cefixime O 200 mg Tablet 10's
  2. Rx
    Taxim O Dry Syrup 50 ml
  3. Ziprax 100 Dry Syrup 30 ml
  4. Zifi CV 200 Tablet 10's
  5. Zifi 100 mg Syrup 30 ml
  6. Zifi 100 mg Syrup 30 ml
  7. Taxim-OF Tablet 10's
  8. Zifi O 100 DT Tablet 10's
  9. Taxim O Drop 10 ml
  10. Taxim O Dry Syrup Delicious Pineapple 30 ml

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